Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

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Figure 3.
Figure 3.

Bimodal distribution of the HCT count for 273 PWMs with respect to the GC content of HCTs. PWMs with more than 400 HCTs (28.6%, black) have HCTs that are either AT-rich (5.5%) or GC-rich (23.1%). The GC content was calculated for the entire span of the HCT, but avoiding coding and repetitive sequences.

This Article

  1. Published in Advance April 2, 2010, doi: 10.1101/gr.104471.109 Genome Res. 20: 565-577

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