Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3.
Figure 3.

Expression coregulation of CNS developmental- and dopamine signaling–related genes and the effect of age on gene expression levels. The expression level of each gene (right of graphs) in individual subjects is depicted in chronological order by age. (Left) Normal subjects; (right) subjects with schizophrenia. (Top panels) Genes related to neurite outgrowth; (middle panels) genes related to dopamine synaptic transmission; (bottom panels) genes related to neuronal differentiation, morphogenesis, and migration. Pearson correlation coefficients (Pearson r-values) for the linear association with age in normal subjects and those with schizophrenia are provided in Table 3.

This Article

  1. Genome Res. 20: 403-412

Preprint Server