Nitrogen depletion in the fission yeast Schizosaccharomyces pombe causes nucleosome loss in both promoters and coding regions of activated genes

Overview of gene expression changes after nitrogen starvation. (A) Overlap between genes that were up-regulated 20 min after the onset of nitrogen starvation (this study) and genes that were up-regulated after 60 min or defined as transiently induced genes (Mata et al. 2002). P-values were calculated using Fisher's exact test. (B) Genomic distribution of up-regulated and down-regulated genes. The x-axis shows the position of the gene in base pairs from the left end of each chromosome, and the y-axis shows the change in gene expression log₂ ratio after 20 min of nitrogen starvation. (▲) Significantly up-regulated genes; (▼) significantly down-regulated genes. (Red lines) A loess curve fitted to the gene expression log₂ ratios.