Dynamic changes in the human methylome during differentiation

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Figure 6.
Figure 6.

Differentially methylated regions (DMRs) in hESCs and hESC-Fibros. (A) Scatterplot of methylation level in hESCs (x-axis) versus in hESC-Fibro (y-axis). The red line indicates the cutoff of 5 SDs. The distribution is very similar in the two cell types, with a correlation coefficient of 0.879. (B) Examples of DMRs found in the pluripotence-associated transcription factors TCF3, POU5F1, and KLF4.

This Article

  1. Published in Advance February 4, 2010, doi: 10.1101/gr.101907.109 Genome Res. 20: 320-331

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