Effect of the cross-mapping correction on mapping weights. The weight ratio is defined as the weight calculated by the cross-mapping correction strategy divided by the corresponding weight under an equal-weight strategy (see text for more detail). The more a weight ratio differs from unity, the larger the cross-mapping correction. (A) The cumulative distribution of the weight ratios, revealing that most weights are reduced in comparison to the equal-weight strategy, while a few weights are greatly increased. (B) A two-dimensional binning plot of the count of each short RNA sequence and the weight ratio, using a logarithmic color scheme to represent the number of mapping events in each bin.
