A new strategy for genome assembly using short sequence reads and reduced representation libraries

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

UCSC Genome Browser screen shot highlighting read coverage for each sequenced library. The top track represents theoretical fragments generated by in silico EcoRI restriction enzyme digestion. Read density tracks are color-coded by library as red (1–4 kb), green (4–7 kb), purple (7–9 kb), or blue (9–30 kb). The following four tracks are reads from each individual library aligned back to the dm3 reference using Illumina's short read aligner, ELAND, with standard parameters.

This Article

  1. Genome Res. 20: 249-256

Preprint Server