Figure 2.
Evolution of genome coverage across time. (Black) FAIRE; (red) MAINE. Overlapping coverage, i.e., the number of nucleotides that are covered by five reads and more in both FAIRE- and MAINE-seq, is shown in green. The genome is consistently more covered with FAIRE-seq, which demonstrates a high content in protein-free DNA, especially at 18 hpi. A t-test was performed and showed that the observed differences are significant, with P < 0.001 for all time points (**) except 6 hpi, where P < 0.01 (*). Overlapping coverage increasing at the latest time point is consistent with a progressive degradation of the parasites synchrony across time.
