Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation

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Figure 3.
Figure 3.

Observed cumulative bias of various amplification methods. X-axis denotes the probe GC content. Y-axis denotes the cumulative bias score, which captures the cumulative signal attenuation over the 50 bins of local CpG density (for definition, see Methods). Each line represents a different amplification strategy.

This Article

  1. Genome Res. 20: 1719-1729

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