RNA synthesis precision is regulated by preinitiation complex turnover

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Figure 7.
Figure 7.

Relationship between Mot1-regulated genes and CUT and SUT RNAs. The diagrams illustrate the two significant relationships detected between Mot1-mediated gene expression and noncoding transcription. Mot1-activated genes tend to have an overlapping CUT transcribed in the antisense direction. The CUT transcripts initiate within the transcribed region of the Mot1-activated gene, ∼40 bp on average upstream of the Mot1-activated gene termination site. In contrast, Mot1-repressed genes tend to have an overlapping antisense SUT. These SUTs initiate ∼40 bp on average downstream from the termination site for the Mot1-repressed gene.

This Article

  1. Genome Res. 20: 1679-1688

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