A comprehensive survey of 3′ animal miRNA modification events and a possible role for 3′ adenylation in modulating miRNA targeting effectiveness

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

Unambiguous uridine addition occurs predominantly in miRNAs derived from 3′ arm of precursor miRNA. Percentages of unambiguous additions for each single nucleotide are colored according to which arm of the precursor miRNA the addition event originates from. Uridine addition bias is observed across all analyzed vertebrate libraries, species and tissue are labeled on the right.

This Article

  1. Genome Res. 20: 1398-1410

Preprint Server