Detection of nonneutral substitution rates on mammalian phylogenies

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Figure 5.
Figure 5.

Distributions of subtree scores for the primate and glires clades. Cumulative distribution functions (CDFs) of scores for selected annotation classes as computed by the subtree test for the primate (A) and glires (B) clades. As in previous figures, CONACC scores computed by the LRT method are shown, but in this case, scores are computed in a 10-bp sliding window. In both figures most distributions are significantly different from the AR distribution by a two-sided Mann-Whitney U test even when the curves appear very similar, because the data sets are generally quite large (exceptions are phastCons and TFBS in A and 5′ flank and TFBS in B).

This Article

  1. Genome Res. 20: 110-121

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