Cumulative accrual of phenotyped DNA samples for the asthma DBP. Unlike the membership of the overall asthma datamart (N = 131,230), the pool from which patients were drawn was first restricted to those seen at the Brigham and Women's Hospital where the Crimson system was first deployed, as the second Crimson site (Massachusetts General Hospital) came online only in late 2008. Additional restrictions included age (<45 yr, >15 yr) and smoking status (nonsmoker or ex-smoker). Projected (A) and actual (B) accrual rates for four groups: LCA (Low-utilizer Caucasian American); LAA (Low-utilizer African American); HCA (High-utilizer Caucasian American); HAA (High-utilizer African American). Utilization here is defined by the absence of hospital admissions (low utilizer) in contrast to at least two admissions (high utilizer). As shown above, the recruitment of low utilitzers (LCA and LAA) started later than the recruitment of the high utilizers. Nonetheless, the projected recruitment rates and the actual recruitment rates are very similar.
