Figure 1.
Pipeline for the detection of CNVs based on analysis of read depth (RD). (A) RD was determined by counting the start position of reads in nonoverlapping windows of 100 bp. (B) Events were detected using a custom CNV-calling algorithm, event-wise testing (EWT). (C) Each event was examined in multiple genomes in order to distinguish polymorphic events (CNVs) from the majority of events that were found to show a similar copy number change in all five genomes in this study (i.e., monomorphic events).
