Identification of rare cancer driver mutations by network reconstruction

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Figure 5.
Figure 5.

The relationship of genes mutated in colon cancer module 6. (Red oval) Genes mutated in colon cancer module 6; (aqua ovals) colon module 6 genes mutated in breast cancer or glioblastoma; (orange ovals) unmutated colon module 6 genes; (yellow ovals) genes not present in colon cancer module 6. (Black lines or touching ovals) Functional protein relationships; (blue lines) transcriptional relationships. Dotted lines depict movement of beta-catenin (CTNNB1) from the cytoplasm to nucleus.

This Article

  1. Published in Advance July 2, 2009, doi: 10.1101/gr.092833.109 Genome Res. 19: 1570-1578

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