Figure 4.
Haplotype association mapping of acetaminophen-induced liver injury in the mouse. Serum ALT at 4 h (A) and 24 h (B) after acetaminophen (300 mg/kg) treatment was used to identify genomic intervals significantly associated with liver injury. Peaks (numbered, see Table 1) indicate a significant logP association score at each 3-SNP marker window. Marker colors indicate chromosome number across the mouse genome.
