Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

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Figure 1.
Figure 1.

Maximum serum ALT fold change measured in human volunteers taking daily oral doses of acetaminophen. The peak ALT fold change over baseline reached over the course of treatment by each subject in the UNC cohort is shown. Subjects were considered responders (N = 34) if peak serum ALT reached greater than 1.5-fold (line) higher than the subject's baseline value.

This Article

  1. Genome Res. 19: 1507-1515

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