Figure 3.
Selection of promoter methylation markers. (A) Outline of the pipeline used to identify markers. (B) Heat-map of the selected markers; promoter AMS for newborn melanocytes (NBMEL), adult melanocytes (ADMEL), and eight melanoma cell strains, and CpG ratio in each of six regions is represented; absolute gene expression as well the expression relative to newborn melanocytes (NBMEL) are displayed; gene symbols of differentially expressed genes are shown on the right side in order of significance, top to bottom from the left column. Two alternative promoters are displayed for LYNX1 (see Supplemental Table S1).
