Number of zebrafish gene pairs derived from WGD showing changes in regulatory control versus changes in protein function
Click on table to view larger version.
-
Spatial expression data were obtained in this study or from ZFIN, temporal expression data were obtained from Wilkins et al. (S Wilkins, M Kerr, M Köppen, B Gardiner, D Taylor, C Simons, M Landsberg, S Grimmond, C Heisenberg, and A Perkins, in prep.) and Mathavan et al. (2005), domain architecture of proteins encoded by WGD-duplicates was determined using InterProScan against the Pfam-A database, and subcellular localization was determined using SignalP (Bendtsen et al. 2004) and TMHMM (Krogh et al. 2001). Only 7% of gene pairs with spatial and/or temporal expression were identical in expression, while 76% of gene pairs with domain architecture and/or subcellular localization information were identical in protein annotation.
