High-resolution analysis of epigenetic changes associated with X inactivation

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Figure 5.
Figure 5.

Kinetics of H3K27me3 over chromosome X during XCI in XT67E1 cells, showing a chromosome-wide increase of H3K27me3 during XCI. (A) H3K27me3 profiles over chromosome X in XT67E1 cells. Chromosome X is subdivided in bins of 1 Mb, followed by counting of the number of tags per bin. undiff, undifferentiated. (B) Subtraction tracks of the H3K27me3 profiles shown in A at a higher resolution (bins of 100 kb). Increase of H3K27me3 as compared to undifferentiated cells is indicated in blue, decrease in red.

This Article

  1. Published in Advance July 6, 2009, doi: 10.1101/gr.092643.109 Genome Res. 19: 1361-1373

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