Figure 6.
Regions flanking sites of CTCF binding are also enriched in soluble chromatin. The plot shows that the strong preference for CTCF clusters to partition into soluble SRD and MND fractions is shared by sequences flanking CTCF binding sites and extends for several kilobases. Note that median log2R values only return toward the median for the entire data sets after 50 kb and that sequences detected by probes lying in regions more than 75 kb from any sites of CTCF binding are actually enriched in insoluble chromatin (Kruskal-Wallis; χ2 = 534.5, df = 9, P < 0.0001).
