Overlapping pools for high-throughput targeted resequencing

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Figure 2.
Figure 2.

Identification of carriers. For log pools, 345 out of a total of 539 single carrier identifications were correct across all coverage profiles, 311 out of 421 were correct (≥15× coverage), 266 out of 302 were correct (≥15× coverage), and 206 out of 223 were correct (≥20× coverage). For ECC pools, 783 out of a total of 1597 single carrier identifications were correct across all coverage profiles, 637 out of 1109 were correct (≥10× coverage), 441 out of 633 were correct (≥15× coverage), and 321 out of 405 were correct (≥20× coverage).

This Article

  1. Genome Res. 19: 1254-1261

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