DNA Sudoku—harnessing high-throughput sequencing for multiplexed specimen analysis

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4.
Figure 4.

Simulations of decoder performance in different CRT pooling designs with 40,320 specimens. (A,B) The effect of increasing the weight with 384 barcodes. (C,D) The effect of increasing the number of barcodes with five pooling windows. (A,C) The probability of correct decoding as a function of d0 with different pooling designs. (Gray line) 99%. (B,D) The expected number of ambiguous specimens due to decoding errors as a function of d0 and different pooling designs.

This Article

  1. Genome Res. 19: 1243-1253

Preprint Server