Table 2.
List of mutations found in S. pneumoniae isolates selected for linezolid resistance
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aAll S. pneumoniae loci number (spr#) are according to the annotation of R6.
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bThe genome of this mutant was not sequenced. Only the genes found mutated in 1974M2 were PCR amplified and sequenced in 1974M1.
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cWhen the mutations are within coding regions, the change in amino acids is also indicated in italics.
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dIn noncoding sequence. The number preceded by “-“ indicates the position upstream of the ATG.
