Genome sequencing of linezolid-resistant Streptococcus pneumoniae mutants reveals novel mechanisms of resistance

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Figure 2.
Figure 2.

Phylogenetic analysis of a class of RNA methyltransferases related to spr0333. Amino acid sequences of the RNA methyltransferase proteins were aligned using the ClustalW algorithm, and evolutionary trees were constructed using the Neighbor-Joining method with Poisson correction as implemented in the MEGA3.1 package for the most conserved part of the proteins. The reliabilities of each branch point were assessed by the analysis of 1000 bootstrap replicates. A similar tree was obtained also when the whole protein was used for carrying the phylogenetic analysis (not shown).

This Article

  1. Genome Res. 19: 1214-1223

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