New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites

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Figure 1.
Figure 1.

Analysis of predicted interactions between 8-mers from different conservation classes and miRNAs. Closed bars indicate number of predicted interactions between 5′-UTR or 3′-UTR 8-mer sequences (indicated by 5U or 3U, respectively) and 5′- or 3′-ends (indicated by 5P or 3P, respectively) of a full set of mature miRNAs (A), of conserved miRNAs (B), and of nonconserved miRNAs (C). Open bars correspond to mean number of interactions after 1000 shuffling iterations, and error bars indicate standard deviations. (**) P < 5 × 10−5; (*) P < 5 × 10−3; (&) P < 0.05.

This Article

  1. Genome Res. 19: 1175-1183

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