Dynamic reprogramming of transcription factors to and from the subtelomere

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Figure 2.
Figure 2.

Example SBTFs that show dynamic binding preferences as a function of growth or stress condition. (A) SBTFs with TDPs that are significant only in a stress condition. TDPs are shown for each SBTF in two conditions: rich medium (top) and a stress condition (bottom). Genes considered subtelomeric are colored light red in rich-medium binding profiles or dark red in stress profiles. (B) SBTFs that show subtelomeric preference in rich medium. Stress conditions are abbreviated: RAPA (100 nM rapamycin), H2O2 Hi (4 mM hydrogen peroxide), and galactose (2% in YEP medium). Red broken lines, 25 kb. Blue broken lines, peak of background distribution as indicated in Figure 1A.

This Article

  1. Genome Res. 19: 1014-1025

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