Figure 2.
(A) A 2-break on edges (x1, x2) and (y1, y2) from the same chromosome corresponds to either a reversal, or a fission. (B) A 2-break on edges (x1, x2) and (y1, y2) from different chromosomes corresponds to a translocation/fusion. (C) A 2-break on edges (y1, y2) and (x1, ∞) of a linear chromosome corresponds to a reversal affecting a chromosome end x1 and creating a new chromosome end y1. (D) A 2-break on edges (x1, ∞) and (y1, ∞) from different chromosomes models a fusion. Fissions can be modeled as 2-breaks operating on an irregular loop edge (∞, ∞) and an arbitrary regular edge in the genome.
