The difficulty of avoiding false positives in genome scans for natural selection

We reanalyze the genes identified as being positively selected in chimpanzee in Supplemental Table S8 of test set 1 (Bakewell et al. 2007), which reports genes showing a significant signal of positive selection at a genome-wide false discovery rate of 5%. Of the original 59 chimpanzee genes listed here, five had no gene names associated with them and were ignored; another five genes had no coverage in our analysis and hence are not shown. Where different from test set 1, currently approved gene names are given with original IDs in parentheses.

^aLikelihood method.

^bNo approved symbol could be found.