The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host–pathogen interactions

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Table 1.

The APOL gene family is highly polymorphic between primate species

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Table 1.

  • aGene coordinates are given for the following isoforms: APOL1 isoform a, APOL3 isoform 1, APOL4 isoform 1. Gene coordinates for APOL2.1 and APOL7 are given relative to APOL2, and coordinates for marmoset APOL3/L4 are given relative to APOL3.

  • b(+) Indicates a gene with an intact coding region; − indicates that the gene is not present in the genome; and ps indicates a pseudogene with the genotype shown in parentheses.

  • cThe ancestries of marmoset APOL1 and APOL2, and APOL3 and APOL4 are too similar to differentiate.

  • dOnly partial gene sequences were available for baboon APOL1 and marmoset APOL5.

This Article

  1. Published in Advance March 19, 2009, doi: 10.1101/gr.085647.108 Genome Res. 19: 850-858

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