The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host–pathogen interactions

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Figure 3.
Figure 3.

Lineage-specific evidence for positive selection in primate APOL6. A cladogram is shown with maximum-likelihood estimates of lineage-specific dN/dS during primate evolution. Numbers in parentheses are the estimated number of nonsynonymous and synonymous changes, respectively, for each branch. Values of dN/dS are also colored according to the class of dN/dS to which they are predicted to belong (by GABranch analysis): Bolded values belong to class dN/dS = 1.49; bolded, italicized values belong to class dN/dS = 5.92; and nonbolded values belong to class dN/dS = 0.63. Branch lengths in the figure are not proportional to time.

This Article

  1. Published in Advance March 19, 2009, doi: 10.1101/gr.085647.108 Genome Res. 19: 850-858

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