Signals of recent positive selection in a worldwide sample of human populations

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3.
Figure 3.

FST around loci involved in natural variation in pigmentation. For each SNP found to be associated with pigmentation in a genome-wide scan, we plot the maximum pairwise FST between geographic regions in a 100-kb window surrounding the SNP in the HGDP data, as well as a histogram of the null distribution calculated by finding the maximum FST in 100-kb windows surrounding each of 10,000 random SNPs. The dotted lines shows the position beyond which 5% of the random SNPs fall, and the solid lines the position beyond which 1% of the random SNPs fall. Gene names that are starred fall in the 5% tail of at least one comparison, and those with two stars fall in the 1% tail of at least one comparison. Letters are positioned along the y-axis to improve readability. The key in the bottom right panel applies to all panels.

This Article

  1. Genome Res. 19: 826-837

Preprint Server