The functional importance of telomere clustering: Global changes in gene expression result from SIR factor dispersion

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Figure 7.
Figure 7.

Promoters bearing Msn2, Abf1, PAC, and RRPE motifs respond to released SIR complexes. Distribution of expression changes (yku70 esc1 mutant vs. wild type and yku70 esc1 sir3 vs. wild type) is shown for predicted targets of selected yeast transcription factors. Shown are the mean log-fold change plus and minus one standard error (red bar), the median log-fold change (vertical black line), and the 25 and 75 percentiles (gray bar). For reference the distribution of log-fold changes for all ORFs is also shown. For the PAC and RRPE motifs separate distributions were determined for ORFs that are targets of both, of PAC only, and of RRPE only.

This Article

  1. Genome Res. 19: 611-625

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