HapMap methylation-associated SNPs, markers of germline DNA methylation, positively correlate with regional levels of human meiotic recombination

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Figure 1.
Figure 1.

A genome-wide map of human germline methylation. A methylation index (MI) was calculated for each 500 kb of genomic sequence with satisfactory data (no gaps in sequencing and at least 20 known SNPs). The y-axis value and bar color (see color index) demonstrate methylation as the ratio of average genome MI (MIav).

This Article

  1. Published in Advance January 21, 2009, doi: 10.1101/gr.086181.108 Genome Res. 19: 581-589

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