MicroRNA target prediction by expression analysis of host genes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

HOCTAR performance in recognizing previously validated miRNA targets. Comparison of HOCTAR with three sequence-based miRNA target prediction softwares (miRanda, TargetScan, and PicTar) in predicting 56 validated targets of 20 different miRNAs (see text for further details). (A) The panels display, for each of the algorithms analyzed, the ranking position, in a percentile format, of the validated targets selected for the analysis (orange horizontal lines). The distribution of the predictions by HOCTAR tends to be shifted toward the top 50th percentile in comparison to the other three softwares. (B) Summary of the number of validated targets predicted by each of the algorithms.

This Article

  1. Genome Res. 19: 481-490

Preprint Server