Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers

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Figure 1.
Figure 1.

FAIRE-chip signal from MCF7 cells at FOXA1 binding sites. FAIRE-chip signal from MCF7 cells within high confidence FOXA1 recruitment sites from MCF7 cells (lying outside of 1 kb promoters) or specific to LNCaP cells is indicated. A set of randomly selected Forkhead motif-containing regions not bound by FOXA1 in MCF7 cells (Unbound FKHR) as well as randomly selected regions were also used. Data represent mean ± SEM of signals derived from MAT analysis of FAIRE-chip data. *** Indicates a statistically significant difference (P < 0.001).

This Article

  1. Genome Res. 19: 372-380

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