Phylogeny and comparative genomics of telomere-associated (TLO) genes in Candida spp. (A) Cartoon of genomic distribution (note: not precise karyotypes). One gene copy previously identified as TLO14 on the right arm of chromosome 6 in C. albicans (van het Hoog et al. 2007F), is not included in current assemblies or detected using BLAST. Pseudogenes are denoted by ψ. (B) Bayesian phylogeny of TLO nucleotide sequences in C. albicans, C. dubliniensis (prefixed Cd36_), and C. tropicalis (CTRG_05798.3). Branch lengths are proportional to evolutionary change. Monophyly of C. albicans and C. dubliniensis sequences is supported by nonparametric bootstrap values and posterior probabilities from maximum likelihood and Bayesian analyses, respectively. Dotted lines link individual genes to a cartoon of a multiple sequence alignment. Exons are represented by shaded rectangles, putative introns with heavy black lines; spaces between exons represent gaps introduced by multiple alignment. An asterisk (*) denotes a stop codon.
