Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences

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Figure 4.
Figure 4.

Inheritance of stain-specific methylation patterns in F1 hybrids. Two examples (Slc27a6 and Zfp568) for allelic inheritance of stain-specific methylation patterns are shown. In the top panels, hypomethylation scores for BMM of both strains are displayed as described in Figure 3. Averaged methylation levels of individual CpGs were determined by MALDI-TOF analysis at the indicated DMR in BMM, spleen, and testis and are shown color-coded (as in Fig. 3) for parental strains and F1 hybrids. Data are mean values of two to four individual samples.

This Article

  1. Genome Res. 19: 2028-2035

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