Figure 1.
Structural variants of the SVA elements on human chromosome 19. Full-length SVA elements are composed of (CCCTCT)n hexamer simple repeats, an Alu-like region, a VNTR region, and a SINE-R sequence (type 1). Structures of 5′-truncated (type 2), 3′-transducing (type 3), 3′-truncated (type 4), 5′-transducing (type 5), 5′ as well as 3′-transducing (type 6), and SVA2 elements (type 7) are depicted. 5′- and 3′-transduced sequences are indicated as yellow boxes. Heterologous non-SVA sequences in SVA2 elements are illustrated as green box. Asterisks indicate polyadenylation signals. An, polyadenylate.
