Figure 5.
SVA gene-trapping has occurred in other hominids. (A,B) Two different SVA splicing events followed by retrotransposition derived from the TPTE locus on chromosome 21 flanked by a target-site duplication. (A) CH3 SVA containing four processed TPTE exons that utilized AG 336. (B) CH15 SVA containing five processed exons that utilized AG 386. (C) The structure of SVA insertions on CH13, CH18, and CH21 containing the six processed exons from the RHOT1 gene on CH17 with identical target-site duplications.
