BayesCall: A model-based base-calling algorithm for high-throughput short-read sequencing

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Figure 6.
Figure 6.

Average per-cycle error rates and histograms for the number of errors per read. BayesCall had substantially lower error rates in later cycles compared with Bustard, and the difference tended to increase with cycles. Further, BayesCall produced substantially more perfect reads than did Bustard. Alta-Cyclic was run only on the 76-cycle phiX174 data set. BayesCall had a lower average error rate than that of Alta-Cyclic's for all cycles. Note that although Alta-Cyclic is more accurate than Bustard in later cycles, the opposite is true for earlier cycles. (A) Results for the 36-cycle data set. (B) Results for the 76-cycle data set.

This Article

  1. Genome Res. 19: 1884-1895

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