BayesCall: A model-based base-calling algorithm for high-throughput short-read sequencing

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Figure 2.
Figure 2.

Convergence of simulated annealing with 1000, 5000, 10,000, and 20,000 total iterations. The temperature parameter in the ith iteration of simulated annealing is taken as (ni + 1)/n, with n being the total number of iterations. Although using a larger value of n maximizes the likelihood slightly better, the inferred MAP estimate of Sk does not change so much.

This Article

  1. Genome Res. 19: 1884-1895

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