BayesCall: A model-based base-calling algorithm for high-throughput short-read sequencing

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Figure 1.
Figure 1.

The graphical model corresponding to our base-calling algorithm for cluster k. The observed random variables are the intensities It,k. Base-calling is done by finding the MAP estimates of St,k. In this example, the window size is 3, with l = r = 1. See Methods for a detailed description.

This Article

  1. Published in Advance August 6, 2009, doi: 10.1101/gr.095299.109 Genome Res. 19: 1884-1895

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