Recent de novo origin of human protein-coding genes

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Table 1.

Novel human protein-coding genes and supporting evidence.

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Table 1.

  • aLength in codons of longest in-frame (alignable) ORF starting from any ATG in the region.

  • bType of data/database is listed followed by tissue information with database identifiers in parentheses. Underlined accession numbers are full-length, spliced cDNA.

  • cShared disablers are sequence differences shared by chimp, gorilla, orangutan, gibbon, and macaque that eliminate the capacity to produce a protein similar to the human protein.

  • dIndependently sequenced whole genomes: Venter, Watson, HuAA, HuBB, HuCC, HuDD, and HuFF. All data are listed where available.

  • eNot shared with orangutan.

This Article

  1. Published in Advance September 2, 2009, doi: 10.1101/gr.095026.109 Genome Res. 19: 1752-1759

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