Unusual composition of a yeast chromosome arm is associated with its delayed replication

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Figure 1.
Figure 1.

GC content along L. kluyveri chromosomes. (A–H) Shown is the composition of each chromosome (5-kb sliding windows with 2-kb steps) deduced from its DNA sequence (The Génolevures Consortium 2009). (Two solid gray rectangles) Each of the two DNA strands, (underlining) the part of chromosome C corresponding to C-left. The rDNA locus on chromosome H is not represented. (Red rectangle on chromosome C) Position of the MAT locus (enlarged on the right). This locus initially identified by Butler et al. (2004) carries genes that determine either cell type a (MATa1 and MATa2, SAKL0C03674g and SAKL0C03696g, respectively) or alpha (MATalpha1 and MATalpha2, see Methods). It is located between SAKL0C03652g (ortholog of the SLA2 gene of S. cerevisiae) and SAKL0C03718g (ortholog of DIC1 gene of S. cerevisiae) genes. (Vertical black lines) Positions of the Tsk1 retrotransposons (solo LTR, degenerate, and full-length elements) on each chromosomal strand. Note the absence of such elements along C-left.

This Article

  1. Genome Res. 19: 1710-1721

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