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Cover Analysis of genome-wide changes in chromatin modifications during activation of resting human CD4+ T cells reveals that many silent, but inducible, genes are poised for expression (represented by a runner poised on the starting block). (Cover illustration by Raja Jothi. Photo: JRev. DNA brush template: Cynthetic at deviantArt.com. [For details, see Barski et al., pp. 1742–1751.])

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