Most mammalian mRNAs are conserved targets of microRNAs

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.
Figure 6.

Correlation of PCT with mRNA destabilization. (A) Destabilization of human messages with exactly one 7mer-m8 3′UTR site to a transfected miRNA (Grimson et al. 2007). Messages were grouped into six equal bins based on the site PCT. (B) Destabilization of human messages with exactly one 7mer-m8 3′UTR site to a transfected miRNA (Grimson et al. 2007), considering only those sites that were not conserved in either mouse, rat, or dog.

This Article

  1. Published in Advance October 27, 2008, doi: 10.1101/gr.082701.108 Genome Res. 19: 92-105

Preprint Server



Current Issue

  1. March 2026, 36 (3)
  1. Current Issue
  1. Alert me to new issues of Genome Research