Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains

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Figure 4.
Figure 4.

Behavior of C57BL/6J (B6), C57BL/6J-mtAKR/J (B6_AKR), and C57BL/6J-mtFVB/N (B6_FVB) mice on the elevated plus maze. (A) Anxiety was measured by the percentage of entries into open arms, the percentage of time spent in open arms, and the distance walked in open arms. (B) Locomotor activity was recorded as total entries into open and closed arms, the number of times mice entered closed arms, and the distance walked in closed arms. Data represent means and SEM of nine to 12 mice. Asterisks indicate significant differences between strains; : *P < 0.05; **P < 0.01; Mann-Whitney test.

This Article

  1. Genome Res. 19: 159-165

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