genBlastA: Enabling BLAST to identify homologous gene sequences

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Figure 3.
Figure 3.

Grouping of HSPs to represent individual homologous genes in tandem clusters. This figure shows average resolve rate for a total of 30 tandem duplicated gene clusters in the EvsE data set for genBlastA (GB), Cui et al. (2007) (ML), and WU-Blast (WU). Ratio of specific groups was calculated as the number of genes resolved over the total number of genes in each tandem gene cluster. A gene is considered resolved if the HSP group overlaps with only one single gene in WormBase and the span similarity is ≥50%. Gapped and ungapped represent two independent BLAST results using either gapped setting or ungapped setting. GB alpha value is 0.5. ML distance threshold is 1000. Error bars, SE. (***) Statistical significance (P < 0.001) by paired Student’s t-test.

This Article

  1. Genome Res. 19: 143-149

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