
In vivo competitive index (CI) of the P. aeruginosa STM PALES_45041 (within LESGI-5), PALES_25621 (within LES prophage 5), PALES_13261 (within LES prophage 3), and PALES_08021 (within LES prophage 2) grown for 7 d in the rat lung in competition with the wild-type LESB58 strain. Each circle represents the CI for a single animal in each group. A CI of less than 1 indicates an attenuation of virulence. The geometric mean of the CIs for all rats is shown as a solid line and statistically significant P-value is indicated with an asterisk (*P < 0.001 using the Mann-Whitney sum test).











