Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa

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Figure 4.
Figure 4.

In vivo competitive index (CI) of the P. aeruginosa STM PALES_45041 (within LESGI-5), PALES_25621 (within LES prophage 5), PALES_13261 (within LES prophage 3), and PALES_08021 (within LES prophage 2) grown for 7 d in the rat lung in competition with the wild-type LESB58 strain. Each circle represents the CI for a single animal in each group. A CI of less than 1 indicates an attenuation of virulence. The geometric mean of the CIs for all rats is shown as a solid line and statistically significant P-value is indicated with an asterisk (*P < 0.001 using the Mann-Whitney sum test).

This Article

  1. Genome Res. 19: 12-23

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