Description of the genomic regions represented on the arrays
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aCategories are mutually exclusive.
bROI, region of interest. Each ROI was 500 bp, typically containing 5 × 50-mer probes.
cMost genes were represented by multiple ROIs. All genome annotations were from Ensembl genome browser (Homo sapiens release 45.36g based on NCBI 36). Pseudogene annotations were obtained from www.pseudogene.org.
dROIs in nonpromoter categories were biased toward CpG islands annotated in the Ensembl genome browser.
eCpGo/e was calculated as (no. of CpGs × sequence length)/(no. of Cs × no. of Gs).
f94% of promoter-ROIs are located within 800 bp of the annotated TSS.
NA, Not available.
